Basic information
The Department of Medical Chemistry and Clinical Biochemistry is a specialized medical, scientific research and educational institution, a joint workplace of Charles University, 2nd Faculty of Medicine and the University Hospital in Motol.
Our workplaces are located on the ground floor, 2nd and 3rd floor of block G of the laboratory complement, between the children's and adult parts of the hospital. Access to the secretariat of the institute and the head, to most laboratories and offices is provided from node 2G - (2nd floor, building G). The reception of ÚLCHKB biological material is also located here.
ÚLCHKB performs a wide range of laboratory tests in the field of clinical biochemistry, pharmacology, toxicology, immunology, endocrinology, etc. for outpatient and inpatient departments of the Motol University Hospital, but also for other departments within the Czech Republic and abroad, continuously 24 hours a day, 7 days a week.
Other contacts
Chief laboratory assistant
M.Sc. Martina Bunešová, MBA
(224) 435 318
martina.bunesova@fnmotol.cz
Secretariat
Bc. Michaela Hrusova, DiS
(224) 435 302
michaela.hrusova@fnmotol.cz
Jaroslav Hauerland
(224) 435 301
jaroslav.hauerland@fnmotol.cz
Management and staff
Knowledge
The head
Prof. MD Richard Pruša, CSc., EuSpLM
tel .: (224) 435 300
Email: richard.prusa@fnmotol.cz
Secretariat of the Head
Bc. Michaela Hrusova, DiS
tel .: (224) 435 302
Email: michaela.hrusova@fnmotol.cz
Jaroslav Hauerland
tel .: (224) 435 301
Email: jaroslav.hauerland@fnmotol.cz
Medical Deputy Chief
MUDr. Jana Čepová, Ph.D., MBA
tel .: (224) 435 332
Email: jana.cepova@fnmotol.cz
Quality manager
Doc. Ing. Karel Kotaška, Ph.D., EuSpLM
tel .: (224) 435 341
Email: karel.kotaska@fnmotol.cz
Head of School
Doc. Ing. Karel Kotaška, Ph.D., EuSpLM
phone: 224 435 341
Email: karel.kotaska@fnmotol.cz
Deputy Head of Science and Research
Doc. Ing. Eva Klapková, Ph.D.
tel .: 224 435 325
Email: eva.klapkova@fnmotol.cz
Chief laboratory assistant
M.Sc. Martina Bunešová, MBA
tel .: (224) 435 318
Email: martina.bunesova@fnmotol.cz
Doctors:
MD Jana Čepová, Ph.D., MBA
tel .: (224) 435 332
MUDr. Tomas Franek, Ph.D.
tel .: (224) 435 341
MD Tomas Moučka
tel .: 224 435 316
MD Julia Anna Werle
tel .: (224) 435 340
MD Martin Hodik
phone: (224) 432 330
Professional university staff in laboratory methods:
M.Sc. Petra Bukovska
tel .: (224) 434 690
Ing. Katerina Dunovska, Ph.D.
tel .: (224) 435 325
MUDr. Ing. Magdalena Fortova, Ph.D.
tel .: (224) 435 345
M.Sc. Jan Illner
tel .: (224) 434 690
Ing. Jiří Hrbacek
tel .: (224) 435 324
Ing. Blanka Jedličková
tel .: (224) 435 319
Doc. Ing. Eva Klapková, Ph.D.
tel .: (224) 435 325
prof. Ing. René Kizek, PhD, MBA
tel .: (224) 435 349
Doc. Ing. Karel Kotaška, Ph.D., EuSpLM
tel .: (224) 435 341
Ing. Jana Meissnerová
tel .: 224
M.Sc. Monika Šramková
tel .: (224) 435 340
Ing. Maria Mellová
tel .: (224) 435 346
Ing. Karolina Padrova, Ph.D.
tel .: (224) 435 340
Clinical pharmacologist:
MD Hundie Tesfaye, Ph.D.
tel .: (224) 435 656
Ambulance
METABOLIC AMBULANCES OF ÚLCHKB
The ÚLCHKB metabolic outpatient clinic provides diagnostics and treatment for patients with disorders lipid metabolismWith disorders of bone metabolism (osteoporosis), with defects nurse .
The metabolic outpatient clinic provides consulting services for the University Hospital in Motol. Blood and urine samples are taken here for laboratory tests and clinical examinations of outpatient patients.
Patients are sent to the ÚLCHKB outpatient clinic by general practitioners or doctors of other specialties. They are ordered with a recommendation either by phone (224) between 9:00 and 12:00 or in person.
The ÚLCHKB metabolic ambulance is located in ground floor of building G. Office hours are from 6:00 to 14:00.
Sampling is performed on working days from 6:00 to 8:00.
Collection room:
Nurses: Alena Hálová
Julia Kmínková
The | Subscriptions | Office hours | Doctors present | |
Monday | 6:00 - 8:00 | 6:30 - 11:00 | 11:30 - 14:00 | Prim. MUDr. Jana Čepová, Ph.D., MBA |
Tuesday | 6:00 - 8:00 | 6:30 - 11:00 | 11:30 - 14:00 | Prim. MUDr. Jana Čepová, Ph.D., MBA |
Wednesday | 6:00 - 8:00 | 6:30 - 11:00 | 11:30 - 14:00 | Prim. MUDr. Jana Čepová, Ph.D., MBA |
Thursday | 6:00 - 8:00 | 6:30 - 11:00 | 11:30 - 14:00 | Prim. MUDr. Jana Čepová, Ph.D., MBA |
Friday | 6:00 - 8:00 | 6:30 - 11:00 | 11:30 - 13:00 | Prim. MUDr. Jana Čepová, Ph.D., MBA |
The structure of the institute
ÚLCHKB consists of the department of logistics and receipt of biological material, the central biochemical laboratory, the RIA laboratory, the department of clinical pharmacology (TDM and pharmacokinetics), the department of immunochemistry and serology, the department of special methods (HPLC, AAS, FTIR, LC-MS), urine laboratories and laboratories for the analysis of urinary stones, there is also a detached workplace for the determination of chlorides in sweat and a section for POCT. ÚLCHKB provides over 220 different laboratory tests. It examines an average of 2500 biological samples per day, ie 750 examinations / month in a continuous three-shift operation. A number of examinations are also performed for other external medical facilities, eg MTX, cyclosporin A, busulfan, tacrolimus, sirolimus, lead, platinum, IGF-000, determination of antifungals, etc. metabolism, eating disorders in the sense of obesity and malnutrition.
Science and research
Free radical biochemistry, oxidative cell damage and antioxidant systems. Biochemical tissue remodeling and wound healing. Study of connective tissue collagen proteins and their proteinases. Biomarkers of cancer and degenerative diseases. Trace elements, vitamins A, E, K, D. Nutritional hormones. Bone metabolism. Sepsis biomarkers (MDW and MxA protein).
The projects of the Institute of Medical Chemistry and Clinical Biochemistry of the 2nd Medical Faculty of Charles University are focused on research of new biomarkers in malignant tumors (bottoms 2, -2proPSA, mindin, sarcosine), inhibin A as a marker of VVV in prenatal screening, marker of diabetic nephropathy , marker of acute kidney damage (NGAL), monitoring of drug levels (busulfan, ganciclovir), determination of vitamin K1 and K2 levels (MK-4, MK-7) by LC / MS and HPLC, determination of markers of liver fibrosis (hyaluronic acid, collagen, TIMP), determination of selenium and manganese in cerebrospinal fluid using AAS and determination of reference limits in children, research of markers of oxidative stress and lipoperoxidation by fluorimetry and liquid and gas chromatography. The aim of the research is also to determine the reference limits of vitamin K1, MK4 and MK7 and to correlate the values with the values of subcarboxylated osteocalcin and other bone markers.
ÚLCHKB research projects focus on sexual differentiation disorders (steroid 21-hydroxylase, inhibins), nutritional hormones (amylin, orexins), biochemical transplant monitoring (IL-6, cystatin C, alpha-GST), biochemical monitoring of cancer (cathepsin B ), biomarkers of wound healing (metalloproteinases).
Documents to download
Current offer The services we provide in the field of laboratory medicine can be found in the laboratory manual of our institute. It is primarily intended for healthcare professionals, especially doctors and nurses, but the patient can also learn a lot of important information here. The laboratory manual is prepared in accordance with the ČSN EN ISO 9001 standard, taking into account the ČSN EN ISO 15189 standard and the SAK accreditation standards.
Laboratory manual it contains basic information about the organization of the laboratory and the range of services offered, a manual for taking primary samples, information about the pre-analytical phase of the examination, information about issuing results, communication with the laboratory and of course basic information about individual examinations.
Laboratory manual 2024
Appendix No. 1 - samples of request forms
Appendix No. 2 - List of laboratory examinations
Appendix No. 3 - Reference range depending on ethnicity
Appendix No. 4 - Reference range in minority populations
- Chlorides in sweat
- Medicines requisition form
- Urine request
- Routine request
- Statim - request form
- CT
- HIV application
Reference range in minority groups
Pre-analytical manual
- Pre-analytical manual (176,42 KB)
For the professional public
- Seminars and professional events
- Teaching
- Publications
Publications
The 14th and 15th updates of the publication are just coming out
Guide to laboratory findings
The editor of this long-term project is the head of the institute prof. MD Richard Pruša, CSc. and a number of experts from our institute and other workplaces of the Motol University Hospital participate in it as an author. The publication is published by Raabe.
More on www.raabe.cz/
For the publication of the Guide to Laboratory Findings, the Czech Society of Clinical Biochemistry was prof. Průš was awarded the prize "For teaching and education in the field of clinical biochemistry and laboratory medicine". Prof. Průša thanks all colleagues who participated in the creation of the publication.
In recent years, important teaching texts have been published, which are intended not only for students of medical faculties at Charles University, but I can also be a useful study material for students of other universities and also a practical tool for clinical laboratory staff.
Bioanalytical chemistry in examples and exercises
Jiří Kukačka, Eva Klapková, Karel Kotaška
Published by Charles University in Prague
Karolinum publishing house
Prague 2010
ISBN 978-80-246-1853-1
1st edition
Bioanalytical chemistry in examples and exercises is a modern multidisciplinary textbook (exercise book) primarily created for students of the bachelor's degree in Medical Laboratory, which is taught at the 2nd Faculty of Medicine, Charles University, but is also intended for other students of bachelor's and master's courses in medicine, pharmaceuticals, science, medical or chemical-technological faculties that train specialists in the field of biological material analysis, especially specialists for work in clinical laboratories. The textbooks are divided into 25 chapters with a practical appendix with useful relationships and chemical-analytical tables. Selected, didactically related chapters will perform calculations in all areas of practical analytical activities in medical laboratories from basic preparation and preparation of solutions, expression of solutions, preparation of buffers, through titration stoichiometry to calculations in special analytical instrumental methods or processing of analytical results. Much of the more than 530 examples are solved in detail, including an explanation of the logical procedure. Unsolved examples are presented together with the results, for their solution, for example, in self-study, knowledge of basic mathematics and a calculator with several functions will suffice.
This unique textbook won Award of the Committee of the Czech Society of Clinical Biochemistry for education for the year 2010.
Case reports and brief chapters from clinical biochemistry
Richard Průša and team
Published by the Institute of Clinical Biochemistry and Pathobiochemistry,
Charles University, 2nd Faculty of Medicine and Motol University Hospital
Prague 2009
ISBN 978-80-87347-01-0
1st edition
Case reports and brief chapters from clinical biochemistry is an engaging textbook of clinical biochemistry for students of the 5th year of medical faculties. A number of experts participated as authors. The publication was created with the support of ROCHE Diagnostics.
General and clinical biochemistry for bachelor's fields of study
Petr Štern and the team of authors
Published by Charles University in Prague
Karolinum publishing house
Prague 2011
ISBN 978-80-246-1979-8
2nd, revised edition
This publication is the second updated and expanded edition of the textbook, which is intended for students of Czech medical faculties. A number of leading experts from the 1st Medical Faculty of Charles University, the 2nd Medical Faculty of Charles University, the Medical and Pharmaceutical Faculty of Charles University in Hradec Králové, the Faculty of Chemical Technology of the University of Pardubice and workplaces from Olomouc, Ostrava and Třinec participated in the creation of these scripts. The script contains four main chapters, namely the chemical repetitorium, biochemistry of selected groups of natural substances, metabolic processes and their disorders and the basics of clinical biochemistry (laboratory activities in clinical biochemistry, technology in clinical biochemistry, examination methods in clinical biochemistry). The publication includes a CD-ROM with other study materials in the field of clinical biochemistry.
Other
Quality management
The Institute of Medical Chemistry and Clinical Biochemistry of the 2nd Medical Faculty of Charles University is a part of the accredited medical facility of the University Hospital in Motol. The medical facility was successfully investigated Joint Accreditation Commission of the Czech Republic and met the criteria for management and continuous quality improvement according to national accreditation standards. The validity of the certificate registration number 1306 on the granting of accreditation is from 29 January 1 to 2021 January 28.
CONFIRMATION OF REGISTRATION
NASKL - Register of Clinical Laboratories a
CERTIFICATE OF COMPLIANCE WITH AUDIT CONDITIONS II,
The Institute of Medical Chemistry and Clinical Biochemistry of the 2nd Medical Faculty of Charles University and the Motol University Hospital is registered in the Register of Clinical Laboratories of the National Authorization Center for Clinical Laboratories at ČLS JEP and involved in the quality improvement program in health care guaranteed by the Ministry of Health. 0078. 801. 31.
On 5 May 5, the Institute of Medical Chemistry and Clinical Biochemistry successfully met the conditions of the R2021 Audit for Expertise 3 - Department of Clinical Biochemistry, NASKL and holds a certificate No. AR801-3-052-2021-0078 valid for three years from the date of issue.
Annual Report
Gallery
Contact
V Úvalu 84
150 06 Prague 5
tel .: 224 435 300
fax: 224 435 320
Email: biochemie@fnmotol.cz
location: BUILDING G, 2nd floor